Tuberous sclerosis complex (TSC) is a neurocutaneous disease inherited in an autosomal dominant pattern with variable penetration.This case beetroot birkenstock report is of a 12-year-old boy who presented with complaints of headache, vomiting, and fits.His neurocutaneous stigmata combined with radiological imaging led us to the diagnosis of TSC wi
Abstract Background Dried blood spot (DBS) testing provides here an alternative to phlebotomy and addresses barriers to accessing healthcare experienced by some key populations.Large-scale evaluations of DBS testing programs are needed to understand their feasibility.This study evaluated the implementation of a state-wide DBS HIV and hepatitis C vi
Computational small molecule docking into comparative models of proteins is widely used to query protein function and in the development of small molecule therapeutics.We benchmark RosettaLigand docking into comparative models for nine proteins built during CASP8 that contain ligands.We supplement the study with 21 additional protein/ligand complex
Background: Discovery of bioactive natural products are instrumental for development of novel antibiotics.The discovery and development of natural products such as penicillin represented a major milestone in the treatment of bacterial infections.Currently, many antibiotics have lost their relevance in clinics due to the emergence of drug-resistant